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Natalie A Bezman Selected Research

elotuzumab

6/2022Combination elotuzumab and lenalidomide treatment efficacy is dependent on crosstalk between NK cells, monocytes and myeloma cells.
10/2019Enhanced SLAMF7 Homotypic Interactions by Elotuzumab Improves NK Cell Killing of Multiple Myeloma.
1/2018Antibody-Dependent Cellular Phagocytosis by Macrophages is a Novel Mechanism of Action of Elotuzumab.
5/2017PD-1 blockade enhances elotuzumab efficacy in mouse tumor models.
1/2017The anti-SLAMF7 antibody elotuzumab mediates NK cell activation through both CD16-dependent and -independent mechanisms.

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Natalie A Bezman Research Topics

Disease

5Multiple Myeloma
06/2022 - 01/2017
5Neoplasms (Cancer)
12/2020 - 12/2007
4Infections
06/2014 - 05/2012
3Virus Diseases (Viral Diseases)
05/2012 - 10/2010
2Lymphopenia (Lymphocytopenia)
02/2011 - 03/2010
1Disease Progression
01/2021
1Cytomegalovirus Infections (Inclusion Disease)
06/2014
1Inflammation (Inflammations)
05/2013
1DiGeorge Syndrome (Syndrome, DiGeorge)
10/2010
1Polycythemia (Erythrocytosis)
12/2007
1Hypoxia (Hypoxemia)
12/2004
1Teratoma (Teratoid Tumor)
12/2004

Drug/Important Bio-Agent (IBA)

5elotuzumabIBA
06/2022 - 01/2017
3Monoclonal AntibodiesIBA
10/2019 - 01/2017
3CytokinesIBA
05/2017 - 05/2012
2MicroRNAs (MicroRNA)IBA
05/2013 - 10/2010
1Lenalidomide (CC 5013)FDA Link
06/2022
1Biomarkers (Surrogate Marker)IBA
01/2021
1Immunoglobulin G (IgG)IBA
10/2019
1Immunoglobulins (Immunoglobulin)IBA
05/2017
1ChemokinesIBA
05/2017
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
01/2017
1AntigensIBA
06/2014
1Interleukin-12 (IL 12)IBA
04/2013
1Antiviral Agents (Antivirals)IBA
04/2013
1STAT4 Transcription FactorIBA
04/2013
1Interleukin-18 (Interleukin 18)IBA
04/2013
1Interleukin-12 Receptors (Interleukin 12 Receptor)IBA
05/2012
1VaccinesIBA
05/2012
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
03/2010
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2007
1Von Hippel-Lindau Tumor Suppressor ProteinIBA
12/2007
1ErythropoietinFDA Link
12/2007
1Proteins (Proteins, Gene)FDA Link
12/2004
1Mutant Proteins (Protein, Mutant)IBA
12/2004

Therapy/Procedure

2Therapeutics
05/2012 - 12/2007
1Duration of Therapy
12/2020
1Drug Therapy (Chemotherapy)
02/2011
1Radiotherapy
02/2011